Background and objectives <p>Post-traumatic stress disorder (PTSD) is a common psychological condition following traumatic events, including physical trauma. In this study, we aimed to determine the prevalence and demographic correlates of PTSD among orthopedic trauma patients.</p> Methods <p>We used a cross-sectional survey design and assessed 200 orthopedic trauma patients, using a self-administered questionnaire. The questionnaire consisted of demographic information and the PTSD Checklist-Civilian Version to determine the prevalence of PTSD.</p> Results <p>The results showed that the prevalence of PTSD was 39%. Females had a higher incidence rate (63%) than males (26%). Females were 1.16 times more likely to suffer from PTSD following trauma as compared to males, with a statistically significant association found between PTSD and female gender. However, the study found no significant association between PTSD and age. Additionally, a high proportion of PTSD participants had comorbid depression.</p> Conclusion <p>Future studies should further explore the demographic and psychological risk factors associated with PTSD following physical trauma.</p>