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Background <p>The prevalence of peripheral arterial disease (PAD) is increasing globally. An increase in PAD in an ageing population inevitably results in an increase in incidence of Chronic Limb Threatening Ischemia (CLTI). Loss of a limb is a life-changing event with immeasurable cost to the individual, while the potential financial benefit of saving a limb is not well documented.</p> Aims <p>The focus of this study was to estimate the cost associated with surgical interventions used in the treatment of CLTI compared with amputation.</p> Methods <p>The cost to treat a CLTI diagnosis in 124 patients was analysed in an acute tertiary referral hospital over a 13-month study period. The analysis included staffing, medical devices used, number of blood components used and the length of stay. Statistical methods included descriptive statistical data and the Mann–Whitney U test.</p> Results <p>The median cost, associated with length of stay, post-amputation and post-revascularisation (hybrid) was €61,313 [IQR = €44,417,&#xa0;€83,331] and €46,573 [IQR = €25,687, €58,554] respectively, <i>p</i> &lt; 0.001.</p> <p>The total median cost for length of stay for amputees in an acute hospital, rehabilitation and a prosthetic limb was €88,820 [IQR = €74,486, €110,248].</p> <p>The median surgical cost of an amputation was €2,064 [IQR = €1,342, €2,866], whilst the median surgical cost of a revascularisation procedure (hybrid) was €5,966 [IQR = €4,380, €7,723], <i>p</i> &lt; 0.001, inclusive of total blood components transfused.</p> Conclusion <p>Revascularisation surgical interventions are more expensive than amputation, however, the length of stay, rehabilitation and prosthetic limb costs, for a patient undergoing a major limb amputation, is significantly more costly.</p>

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Cost analysis of limb salvage: comparing limb revascularisation and amputation in patients with Chronic Limb-Threatening Ischaemia (CLTI) at University Hospital Limerick

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年2月6日

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  • Anne Marie Toomey,
  • Fiona Leahy,
  • Helen Purtill,
  • Norma O’Brien,
  • Emer O’Donovan,
  • Zeeshan Ahmed,
  • Mekki Medani,
  • Tony Moloney,
  • Eamon G. Kavanagh

摘要

Background

The prevalence of peripheral arterial disease (PAD) is increasing globally. An increase in PAD in an ageing population inevitably results in an increase in incidence of Chronic Limb Threatening Ischemia (CLTI). Loss of a limb is a life-changing event with immeasurable cost to the individual, while the potential financial benefit of saving a limb is not well documented.

Aims

The focus of this study was to estimate the cost associated with surgical interventions used in the treatment of CLTI compared with amputation.

Methods

The cost to treat a CLTI diagnosis in 124 patients was analysed in an acute tertiary referral hospital over a 13-month study period. The analysis included staffing, medical devices used, number of blood components used and the length of stay. Statistical methods included descriptive statistical data and the Mann–Whitney U test.

Results

The median cost, associated with length of stay, post-amputation and post-revascularisation (hybrid) was €61,313 [IQR = €44,417, €83,331] and €46,573 [IQR = €25,687, €58,554] respectively, p < 0.001.

The total median cost for length of stay for amputees in an acute hospital, rehabilitation and a prosthetic limb was €88,820 [IQR = €74,486, €110,248].

The median surgical cost of an amputation was €2,064 [IQR = €1,342, €2,866], whilst the median surgical cost of a revascularisation procedure (hybrid) was €5,966 [IQR = €4,380, €7,723], p < 0.001, inclusive of total blood components transfused.

Conclusion

Revascularisation surgical interventions are more expensive than amputation, however, the length of stay, rehabilitation and prosthetic limb costs, for a patient undergoing a major limb amputation, is significantly more costly.