<p>Microstructure evolution, mechanical properties and electrical conductivity of Cu-1Cr-0.1Zr alloy in different states during two-stage cryorolling and aging were investigated. Compared to single-stage aging, intermediate aging promotes the emergence of GP zones in the alloy, accelerating the precipitation of high-density nano-precipitates. Because the intermediate aging precipitated phase has a pinning effect, more nano-twins and dislocation pile-ups were produced, which effectively improved the tensile strength of the alloy. The dense dislocations produced by a second cryorolling provide more nucleation sites, which makes precipitated phases fine and uniform and ensures the lower resistivity of the alloy. After the two-stage cryorolling and aging, the alloy has the optimal properties with a tensile strength of 648.5 MPa, an electrical conductivity of 77% IACS and elongation of 9.4%. The energy-saving and time-efficient two-stage cryorolling and aging provide a feasible way to balance the strength and conductivity of Cu-1Cr-0.1Zr alloy.</p>