<p>To enhance the wear and corrosion resistance of titanium alloy’s surface, Co-Cr-Ti composite coating has been successfully deposited on Ti6Al4V alloy using laser cladding technology. The effect of current, pulse width and frequency was investigated by an orthogonal test and matrix analysis to determine the optimal parameters. A comparative study was systematically conducted between the coating fabricated with optimal parameters and the substrate, focusing on their microstructure, phase constituents, element composition/distribution, microhardness, wear resistance, and corrosion resistance. The composite coating demonstrates a notable enhancement in friction and wear resistance at both room temperature and 500°C, as evaluated through weight loss, coefficient of friction, 3D worn trace morphology, and morphology of worn surfaces, alongside an analysis of the mechanisms. While maintaining higher microhardness and better wear resistance, the Co-Cr-Ti coating has better corrosion resistance, as evidenced by evaluations encompassing open-circuit voltage, corrosion potential, corrosion current density, and the radius of the impedance spectrum. The enhancement of fine-grained microstructure, solid solution formation, and the incorporation of hard phases significantly contribute to the superior properties of the coatings. This work presents a valuable reference for strengthening the wear and corrosion resistance of titanium alloy in automotive service environments.</p>