Schlafbezogene Atmungsstörungen und Schlaganfall
摘要
Sleep-disordered breathing (SDB) is associated with a twofold increased risk of ischemic stroke and augments established cerebrovascular risk factors such as arterial hypertension and diabetes mellitus. In populations at a high risk of stroke, particularly those with carotid atherosclerosis or atrial fibrillation, moderate-to-severe SDB is detectable in up to two thirds of patients. Sleep-disordered breathing worsens functional stroke outcomes and increases the risk of recurrent stroke. While the benefits of positive airway pressure (PAP) therapy during the acute stroke phase remain uncertain, medium- to long-term treatment improves functional recovery, cognitive performance, and reduces the incidence of recurrent stroke as well as cardiovascular and all-cause mortality. Diagnosis and treatment of SDB—particularly through PAP therapy—should be considered an integral component of both primary and secondary prevention of stroke and transient ischemic attack (TIA). This approach is endorsed by current German stroke care guidelines.