In this paper, we study the complex symmetric weighted composition operators on the weighted Bergman space \(\mathcal {A}^2_{\alpha }(\mathbb {H})\) defined over the right half-plane \(\mathbb {H}\) with the reproducing kernels \(K^{\alpha }_w(z)=\frac{2^{\alpha }(\alpha +1)}{(z+{\bar{w}})^{\alpha +2}}\) , as well as on the Hilbert space \(\mathcal {H}_s\) of analytic functions over the unit ball \(\mathbb {B}_n\) with the reproducing kernel \(K_w^s(z)=(1-\langle z, w \rangle )^{-s}\) , where \( \alpha \in \mathbb {N}\) and \( s\in \mathbb {N}^+ \) . As a consequence of our investigation, the open question raised in Huang et al. (Complex Anal Oper Theory 17:119, 2023) is answered completely. Moreover, we provide a complete characterization of the complex symmetry exhibited by the generalized weighted composition-partial differentiation operators, denoted as \(W_{m, \tau , \varphi }\) , defined as \(\begin{aligned} W_{m, \tau , \varphi }f(z):=\tau (z)\partial ^mf(\varphi (z))\;\; \text {for}\;\; f\in \mathcal {H}_s(\mathbb {B}_n) \end{aligned}\) in relation to the conjugation operator \(\mathcal {J}_V\) .
