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<p>Prioritizing patient safety in healthcare is crucial to mitigate adverse drug reactions (ADR) and enhance overall well-being. Despite a significant percentage of hospital admissions being attributed to drug side effects, less than 5% are reported directly by patients. This highlights the necessity for a comprehensive approach to identify, prevent, and monitor ADR. Current prevention methods lack cohesion and alignment, necessitating a holistic platform. This paper proposes a software architecture, employing a service-oriented approach to address ADR concerns. The research follows the design science research methodology, progressing through problem identification, objective definition, design, development, demonstration, and evaluation. Ten essential services are derived from user requirements and organized into a layered architecture combining edge and cloud computing for optimal performance. The platform supports secure and interoperable service deployment, utilizing representational state transfer architecture over hypertext transfer protocol for efficient communication. Continuous Integration and Continuous Deployment are integrated for streamlined implementation. A prototype of the platform was developed to facilitate the evaluation of user acceptance. This research presents a robust software architecture for ADR prevention and monitoring, complete with communication processes and an automated deployment workflow. Evaluation results indicate that the platform has been positively received by users, demonstrating its overall acceptance and potential for effective integration in healthcare settings.</p>

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A holistic platform for adverse drug reaction prevention and monitoring: leveraging service-oriented architecture for tailored healthcare solutions

  • 期刊论文

  • 发表日期：

    2025年4月11日

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  • Aulia-Absari Khalil,
  • Ford Lumban Gaol,
  • Boy Subirosa Sabarguna,
  • Harjanto Prabowo

摘要

Prioritizing patient safety in healthcare is crucial to mitigate adverse drug reactions (ADR) and enhance overall well-being. Despite a significant percentage of hospital admissions being attributed to drug side effects, less than 5% are reported directly by patients. This highlights the necessity for a comprehensive approach to identify, prevent, and monitor ADR. Current prevention methods lack cohesion and alignment, necessitating a holistic platform. This paper proposes a software architecture, employing a service-oriented approach to address ADR concerns. The research follows the design science research methodology, progressing through problem identification, objective definition, design, development, demonstration, and evaluation. Ten essential services are derived from user requirements and organized into a layered architecture combining edge and cloud computing for optimal performance. The platform supports secure and interoperable service deployment, utilizing representational state transfer architecture over hypertext transfer protocol for efficient communication. Continuous Integration and Continuous Deployment are integrated for streamlined implementation. A prototype of the platform was developed to facilitate the evaluation of user acceptance. This research presents a robust software architecture for ADR prevention and monitoring, complete with communication processes and an automated deployment workflow. Evaluation results indicate that the platform has been positively received by users, demonstrating its overall acceptance and potential for effective integration in healthcare settings.