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Objectives <p>The etiology of type A acute aortic dissection (TAAAD) remains unclear. This study aimed to investigate whether the diameter of the common femoral artery (CFA) could serve as a predictor of TAAAD.</p> Methods <p>This retrospective study included 100 patients aged 20–70 years who underwent surgery for TAAAD and had postoperative contrast-enhanced (CT) performed before discharge (TAAAD group). The control group comprised 100 patients who underwent elective surgery for stage ≤ 2 colorectal cancer without preoperative bowel obstruction or perforation between April 2021 and March 2024. CFA diameters measured on postoperative CT images in the TAAAD group were compared with those measured on preoperative CT images in the control group.</p> Results <p>The TAAAD group had a higher proportion of men (76% vs. 59%; <i>p</i> = 0.016), larger body surface area (1.78 [1.65–1.91] vs. 1.70 [1.57–1.83]; <i>p</i> = 0.004), younger age (57 [52–64] vs. 60 [54–67]; <i>p</i> = 0.011), and larger CFA diameter (11.2&#xa0;mm [10.1–12.1] vs. 9.0&#xa0;mm [8.5–9.8]; <i>p</i> &lt; 0.001). Receiver operating characteristic curve analysis for CFA diameter demonstrated good discriminatory performance (area under the curve, 0.88; 95% confidence interval, 0.84–0.93). An optimal cutoff value of 10.5&#xa0;mm yielded a sensitivity of 70% and a specificity of 90%. In multivariable logistic regression analysis, CFA diameter remained significantly associated with TAAAD (OR 5.45, 95% confidence interval 3.47– 9.31, <i>p</i> &lt; 0.001).</p> Conclusions <p>The CFA diameter was significantly larger among patients with TAAAD. These findings suggest that CFA diameter may be associated with the risk of TAAAD.</p>

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Larger common femoral artery diameter is a risk factor for type A acute aortic dissection

  • 期刊论文

  • 发表日期：

    2026年5月9日

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  • Makoto Ikematsu,
  • Keiji Uchida,
  • Tomoki Cho,
  • Kenichi Fushimi,
  • Norihisa Tominaga,
  • Ryo Izubuchi,
  • Tomoyuki Minami,
  • Shota Yasuda,
  • Yoshiyuki Kobayashi,
  • Aya Saito

摘要

Objectives

The etiology of type A acute aortic dissection (TAAAD) remains unclear. This study aimed to investigate whether the diameter of the common femoral artery (CFA) could serve as a predictor of TAAAD.

Methods

This retrospective study included 100 patients aged 20–70 years who underwent surgery for TAAAD and had postoperative contrast-enhanced (CT) performed before discharge (TAAAD group). The control group comprised 100 patients who underwent elective surgery for stage ≤ 2 colorectal cancer without preoperative bowel obstruction or perforation between April 2021 and March 2024. CFA diameters measured on postoperative CT images in the TAAAD group were compared with those measured on preoperative CT images in the control group.

Results

The TAAAD group had a higher proportion of men (76% vs. 59%; p = 0.016), larger body surface area (1.78 [1.65–1.91] vs. 1.70 [1.57–1.83]; p = 0.004), younger age (57 [52–64] vs. 60 [54–67]; p = 0.011), and larger CFA diameter (11.2 mm [10.1–12.1] vs. 9.0 mm [8.5–9.8]; p < 0.001). Receiver operating characteristic curve analysis for CFA diameter demonstrated good discriminatory performance (area under the curve, 0.88; 95% confidence interval, 0.84–0.93). An optimal cutoff value of 10.5 mm yielded a sensitivity of 70% and a specificity of 90%. In multivariable logistic regression analysis, CFA diameter remained significantly associated with TAAAD (OR 5.45, 95% confidence interval 3.47– 9.31, p < 0.001).

Conclusions

The CFA diameter was significantly larger among patients with TAAAD. These findings suggest that CFA diameter may be associated with the risk of TAAAD.