Scholarlink

<p>COVID-19 infection induces widespread endotheliitis, with long-term effects on the vascular system and arterial hypertension that are still under investigation. This study verified the possible correlation between COVID-19 infection and blood pressure control. In the multicenter study presented here, we enrolled 185 hypertensive patients with a positive nasopharyngeal swab for SARS-CoV-2 in the 6&#xa0;months prior to the follow-up visit (Group 1, 90F, age 63.38 ± 10.29&#xa0;years) and 97 hypertensive patients consistently negative for SARS-CoV-2 (Group 2, 49F, age 64.20 ± 10.79&#xa0;years), overlapping in terms of age, sex, weight, and Body Mass Index (BMI). We evaluated the follow-up visit within 12&#xa0;months (T1) and the one prior to the infection (T0). Group 2 had a higher percentage of patients with dyslipidemia and a significantly lower percentage of patients with hypertensive cardiomyopathy (HTN-CM) compared to Group 1. In Group 1, we observed a significant decrease in the number of smokers and an increase in the diagnosis of HTN-CM at T1, with a significant increase in systolic values (134.30 ± 14.93&#xa0;mmHg vs 132.40 ± 16.19&#xa0;mmHg, <i>p</i> &lt; 0.05) and a decrease in diastolic values (78.30 ± 8.77&#xa0;mmHg vs 79.63 ± 8.41&#xa0;mmHg, <i>p</i> &lt; 0.05) compared to T0. Moreover, there was a significant increase in the number of antihypertensive drugs taken at T1 in Group 1, particularly angiotensin-receptor blockers, compared to T0. Finally, at T1 in Group 1, we observed a significant increase in pulse wave velocity (PWV) compared to T0. These findings were absent in Group 2. Patients who contracted the COVID-19 infection showed increased vascular stiffness, hence higher blood pressure values, and needed a greater number of medications for blood pressure control.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

COVID-19 induces greater difficulty in blood pressure control due to increased arterial stiffness

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年11月5日

查看全文
  • Marialuisa S. Marozzi,
  • Ilaria Fucile,
  • Immacolata Panettieri,
  • Mauro Pagani,
  • Rosa Curcio,
  • Francesco Corvasce,
  • Giuseppe S. Falcone,
  • Costantino Mancusi,
  • Raffaele Izzo,
  • Angelo Vacca,
  • Sebastiano Cicco

摘要

COVID-19 infection induces widespread endotheliitis, with long-term effects on the vascular system and arterial hypertension that are still under investigation. This study verified the possible correlation between COVID-19 infection and blood pressure control. In the multicenter study presented here, we enrolled 185 hypertensive patients with a positive nasopharyngeal swab for SARS-CoV-2 in the 6 months prior to the follow-up visit (Group 1, 90F, age 63.38 ± 10.29 years) and 97 hypertensive patients consistently negative for SARS-CoV-2 (Group 2, 49F, age 64.20 ± 10.79 years), overlapping in terms of age, sex, weight, and Body Mass Index (BMI). We evaluated the follow-up visit within 12 months (T1) and the one prior to the infection (T0). Group 2 had a higher percentage of patients with dyslipidemia and a significantly lower percentage of patients with hypertensive cardiomyopathy (HTN-CM) compared to Group 1. In Group 1, we observed a significant decrease in the number of smokers and an increase in the diagnosis of HTN-CM at T1, with a significant increase in systolic values (134.30 ± 14.93 mmHg vs 132.40 ± 16.19 mmHg, p < 0.05) and a decrease in diastolic values (78.30 ± 8.77 mmHg vs 79.63 ± 8.41 mmHg, p < 0.05) compared to T0. Moreover, there was a significant increase in the number of antihypertensive drugs taken at T1 in Group 1, particularly angiotensin-receptor blockers, compared to T0. Finally, at T1 in Group 1, we observed a significant increase in pulse wave velocity (PWV) compared to T0. These findings were absent in Group 2. Patients who contracted the COVID-19 infection showed increased vascular stiffness, hence higher blood pressure values, and needed a greater number of medications for blood pressure control.