Acute pancreatitis manifests as an inflammatory condition, starting with the acinar cells in the pancreas and gradually escalating to widespread inflammation. Hypertriglyceridemia ranks as the third leading reason for acute pancreatitis, following gallstones and alcohol use, making up 2–14% of instances [1]. Numerous research findings indicate that acute pancreatitis triggered by hypertriglyceridemia (HTG-AP, hypertriglyceridemic acute pancreatitis) may lead to increased death rates compared to other acute pancreatitis causes hypertriglyceridemia, characterized by fasting serum triglycerides exceeding (150mg/dL; 1.7mmol/L), and severe hypertriglyceridemia, identified by levels above (885 mg/dL; > 10 mmol/L) [2]. This paper presents an uncommon instance of HTG-AP, triggered by polycystic ovary syndrome and treated with oral contraceptive Drospirenone and ethinylestradiol tablets, where serum triglyceride levels reached an unprecedented 9906.37 mg/dL.
