<p>Zinc (Zn) is a naturally occurring element found in soil within terrestrial ecosystems, and it plays a vital role in plant growth. However, elevated levels of Zn can lead to various physiological and biochemical changes in plants, potentially impeding their growth and productivity. Growing environmental concerns, along with the delicate balance between zinc’s essential benefits and its toxicity, have prompted increased attention from the scientific community regarding its impact on plants and its significance for agricultural sustainability. This review focuses on the latest findings related to the physiological and biochemical processes influenced by high Zn levels, as well as the mechanisms of Zn uptake and transport in the rhizosphere under elevated zinc conditions. The article compiles the mechanisms by which plants absorb, use, and react to Zn. This review article also explains why some plants can not only survive but thrive in high Zn conditions, while excessive Zn levels can still be harmful. By elucidating the intricate interplay between plants and Zn, this review provides insights for future research directions and practical applications to promote sustainable agriculture and environmental health. Moreover, it covers a wide range of issues, such as physiological reactions, molecular mechanisms and ecological implications, to enlighten researchers in environmental science, agriculture and other relevant fields.</p>