<p>This study aimed to compare perioperative and short-term outcomes between multi-arm uniportal robotic-assisted thoracic surgery (URATS) and uniportal video-assisted thoracoscopic surgery (UVATS) in the treatment of non-small cell lung cancer (NSCLC), and to assess the safety and feasibility of URATS. We retrospectively analyzed NSCLC patients who underwent surgery in the Department of Thoracic Surgery at the Affiliated Hospital of Nantong University between April 2023 and April 2025. Patients were grouped by surgical approach (URATS vs. UVATS), with all procedures performed by the same surgical team. Propensity score matching (PSM) was applied using eight baseline variables to reduce confounding and selection bias. Perioperative and short-term postoperative outcomes were compared between matched cohorts. Before matching, 90 patients were in the URATS group and 103 in the UVATS group. After PSM, 57 matched pairs were analyzed, with no significant differences in baseline characteristics (sex, age, BMI, smoking history, comorbidities, surgical site, surgical type, pathological TNM stage; P &gt; 0.05). The URATS group showed statistically significant advantages in lymph node dissection count, lymphadenectomy time, 24/72-hour postoperative pain scores, and postoperative length of stay (P &lt; 0.05), but statistically significantly higher total hospitalization cost (P &lt; 0.05). In this single-center retrospective study with short-term follow-up, URATS is a safe and feasible surgical option for NSCLC. Compared with UVATS, it enables more thorough and efficient lymph node dissection, reduces short-term postoperative pain, and shortens hospitalization. Despite higher costs, URATS may be considered for clinical application in centers experienced in uniportal thoracoscopic and robotic procedures.</p>

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Short-term outcomes of multi-arm uniportal robotic thoracic surgery versus uniportal video-assisted thoracoscopic surgery for non-small cell lung cancer

  • J. Wang,
  • M. M. Xu,
  • Z. J. Chen,
  • Y. Jiang,
  • J. Zhu,
  • S. Wang,
  • J. H. Shi,
  • J. L. Chen

摘要

This study aimed to compare perioperative and short-term outcomes between multi-arm uniportal robotic-assisted thoracic surgery (URATS) and uniportal video-assisted thoracoscopic surgery (UVATS) in the treatment of non-small cell lung cancer (NSCLC), and to assess the safety and feasibility of URATS. We retrospectively analyzed NSCLC patients who underwent surgery in the Department of Thoracic Surgery at the Affiliated Hospital of Nantong University between April 2023 and April 2025. Patients were grouped by surgical approach (URATS vs. UVATS), with all procedures performed by the same surgical team. Propensity score matching (PSM) was applied using eight baseline variables to reduce confounding and selection bias. Perioperative and short-term postoperative outcomes were compared between matched cohorts. Before matching, 90 patients were in the URATS group and 103 in the UVATS group. After PSM, 57 matched pairs were analyzed, with no significant differences in baseline characteristics (sex, age, BMI, smoking history, comorbidities, surgical site, surgical type, pathological TNM stage; P > 0.05). The URATS group showed statistically significant advantages in lymph node dissection count, lymphadenectomy time, 24/72-hour postoperative pain scores, and postoperative length of stay (P < 0.05), but statistically significantly higher total hospitalization cost (P < 0.05). In this single-center retrospective study with short-term follow-up, URATS is a safe and feasible surgical option for NSCLC. Compared with UVATS, it enables more thorough and efficient lymph node dissection, reduces short-term postoperative pain, and shortens hospitalization. Despite higher costs, URATS may be considered for clinical application in centers experienced in uniportal thoracoscopic and robotic procedures.