Scholarlink

<p>The growing complexity and persistence of environmental pollutants necessitate the development of advanced analytical platforms capable of high-resolution detection and mechanistic elucidation. MXene quantum dots (MQDs), with their tunable electronic properties, high surface area, and versatile surface chemistry, have emerged as multifunctional nanostructures that significantly enhance mass spectrometry (MS) performance. This review systematically examines the size-dependent electronic structure, surface-state modulation, and defect-mediated behaviors of MQDs, highlighting how these intrinsic features influence their role as ionization mediators and catalytic enhancers. Key applications in MALDI-TOF and LC–MS for the detection, imaging, and degradation monitoring of environmental contaminants are discussed, emphasizing real-time and multi-omics capabilities. Integration strategies, including heteroatom doping, magnetic functionalization, and hybrid photocatalytic membranes, are analyzed to illustrate improvements in sensitivity, reproducibility, and mechanistic insight. Furthermore, the interplay between MQD structural design, surface chemistry, and electronic properties is explored as a guiding principle for optimizing analytical performance. Collectively, this work establishes a comprehensive framework for the utilization of MQDs as multifunctional enhancers in environmental MS for pollutant detection and mechanistic analysis, representing the first review dedicated to this emerging paradigm.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

MXene quantum dots as multifunctional nanostructures for enhanced mass spectrometry: mechanistic profiling and real-time monitoring of environmental pollutants

  • 期刊论文

  • 发表日期：

    2026年4月9日

查看全文
  • Usamah Sayed,
  • Sanarya Thamer Naser,
  • Subbulakshmi Ganesan,
  • Subhashree Ray,
  • Noor Mazin Basheer,
  • Karthikeyan Jayabalan,
  • Atreyi Pramanik,
  • Apurav Gautam,
  • Hadi Nooriadeh

摘要

The growing complexity and persistence of environmental pollutants necessitate the development of advanced analytical platforms capable of high-resolution detection and mechanistic elucidation. MXene quantum dots (MQDs), with their tunable electronic properties, high surface area, and versatile surface chemistry, have emerged as multifunctional nanostructures that significantly enhance mass spectrometry (MS) performance. This review systematically examines the size-dependent electronic structure, surface-state modulation, and defect-mediated behaviors of MQDs, highlighting how these intrinsic features influence their role as ionization mediators and catalytic enhancers. Key applications in MALDI-TOF and LC–MS for the detection, imaging, and degradation monitoring of environmental contaminants are discussed, emphasizing real-time and multi-omics capabilities. Integration strategies, including heteroatom doping, magnetic functionalization, and hybrid photocatalytic membranes, are analyzed to illustrate improvements in sensitivity, reproducibility, and mechanistic insight. Furthermore, the interplay between MQD structural design, surface chemistry, and electronic properties is explored as a guiding principle for optimizing analytical performance. Collectively, this work establishes a comprehensive framework for the utilization of MQDs as multifunctional enhancers in environmental MS for pollutant detection and mechanistic analysis, representing the first review dedicated to this emerging paradigm.