<p><i>N</i>,<i>N'</i>-diacylhydrazines have recently emerged as highly effective compounds in the fields of insecticides, pesticides, herbicides, and larvicides. Furthermore, they serve as valuable frameworks for the synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles. This review provides a detailed account of synthetic transformations involving <i>N</i>,<i>N'</i>-diacylhydrazines, highlighting the use of various reagents, catalysts, and oxidizing agents, such as oxone, sodium perborate, iodobenzene diacetate, dianisyl telluroxide, polymer-supported periodate, copper acetate, benzeneseleninic acid, (trifluoromethyl)benzene sulfonyl peroxide, sulfated polyborate, sodium carbonate, mercuric acetate, oxalyl chloride, ammonium acetate, potassium superoxide, molecular iodine, and <i>9</i>-fluorenone. Additionally, it offers an overview of diverse methods, techniques, and reaction conditions employed for the synthesis of <i>N</i>,<i>N'</i>-diacylhydrazine derivatives.</p> Graphical abstract <p></p>