Eco-friendly fabrication of silver nanoparticles via Acacia mangium: Exploring antioxidant and antibacterial potentials
摘要
The utilization of plant extracts for synthesizing silver nanoparticles has rapidly emerged as a preferred approach over conventional physicochemical techniques, owing to its ease of use, eco-friendliness, energy efficiency, rapid reaction rate, and enhanced environmental sustainability. This work aimed to produce stable AgNPs derived from Acacia mangium leaf extract (AgNPs-Am) and evaluate their antioxidant and antibacterial efficacy. The formation of AgNPs-Am was verified through analyses including UV–Vis, FTIR, XRD, TEM-SAED, and DLS. AgNPs-Am were optimally produced by mixing 1.0 mM AgNO3 with a leaf extract-to-AgNO3 ratio of 1:2 (v/v) at 70 °C for 3 h. When stored at 4 °C, the synthesized AgNPs-Am remained stable for up to 6 months. FTIR analysis revealed that biomolecules derived from Acacia mangium were effectively anchored onto the AgNPs surface, enhancing their stability. The TEM image showed uniformly spherical AgNPs-Am with a size of 10.57 ± 4.28 nm. An evaluation of antioxidant activity showed that AgNPs-Am had better free radical scavenging activity than Acacia mangium leaf extract. Antibacterial activity tests revealed that AgNPs-Am exhibited strong activity against E. coli and S. aureus, showing inhibition zones of 20.6 and 16.2 mm, respectively. The high bioactivity of AgNPs-Am highlights their potential applications in healthcare, particularly in antimicrobial treatments, as well as environmental management for water purification and pollutant degradation.