Prevalence of Pulmonary Embolism After Bariatric Surgery: a Systematic Review and Meta-Analysis
摘要
Pulmonary embolism (PE) is a potentially life-threatening complication following bariatric surgery. Accurate estimates of its prevalence are essential to inform perioperative risk management and thromboprophylaxis strategies.
MethodsThis systematic review and meta-analysis was conducted in accordance with PRISMA guidelines and registered in PROSPERO. Observational studies and randomized controlled trials reporting postoperative PE among adults (≥ 18 years) undergoing bariatric procedures—including sleeve gastrectomy, Roux-en-Y gastric bypass, and adjustable gastric banding—were included.
ResultsNine studies comprising 1,080,346 patients were included. The pooled prevalence of PE following metabolic-bariatric surgery (MBS) was 3.70 per 1000 procedures (95% CI: 1.71–6.30), with substantial heterogeneity (I² = 99.48%). Subgroup analysis revealed the highest prevalence in open bariatric surgery (7.58 per 1000; 95% CI: 4.10–11.99), intermediate in procedures with unreported surgical approach (2.97 per 1000; 95% CI: 0.76–6.62), and lowest in laparoscopic procedures (1.90 per 1000; 95% CI: 0.00–5.95). Prevalence estimates were similar between prospective and retrospective studies.
ConclusionPE is an uncommon but clinically significant complication after MBS, with risk strongly influenced by surgical technique. These findings emphasize the importance of vigilant perioperative monitoring and tailored thromboprophylaxis, particularly in open procedures.