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Introduction <p>Currently, metabolic bariatric surgery (MBS) is considered the most effective method for achieving substantial and long-term weight-loss in severely obese patients. However, 4 to 40% of bariatric patients do not accomplish optimal results. The study aimed to identify factors contributing to maintain &gt; 50% EWL after MBS at the 10- years observation.</p> Materials and Methods <p>This is a retrospective, multicenter cohort study of patients with obesity who completed 10-years follow-up, undergoing primary laparoscopic MBS surgery in 2007–2014. Data came from 5 bariatric centers. Patients were divided into two groups: patients who achieved more than 50% EWL and those who achieved less than 50% EWL. Uni- and multivariable logistic regression were used to identify predictors of optimal results.</p> Results <p>Out of 368 analyzed patients the median BMI before the surgery was 42.73&#xa0;kg/m2. The most common obesity-related diseases were hypertension (HT) (52.72%) and type 2 diabetes mellitus (T2DM) (30.98%). Sleeve gastrectomy was the most frequently performed procedure (65.22%). The median follow-up was 10.90&#xa0;years. 59,24% patients achieved &gt; 50% EWL. Uni- and multivariable logistic regression analysis confirmed preoperative weigh loss (OR = 1.04; <i>P</i> = 0.03), T2DM (OR = 0.45; <i>P</i> = 0.003), psychiatric history (OR = 0.38; <i>P</i> = 0.01) and one anastomosis gastric bypass (OAGB) (OR = 4.64; <i>P</i> &lt; 0.0001) to have a significant impact on weight loss outcome 10-years after MBS.</p> Conclusions <p>In a 10-year follow-up, patients with greater preoperative weight loss may have a better response to surgery. OAGB emerged as promising type of surgery in terms of weight loss. T2DM and psychiatric history are independent predictors of lower %EWL.</p>

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What Really Matters in Weight Loss after Bariatric Surgery – 10 Years Follow-Up (BARI-10 -POL Study)

  • 期刊论文

  • 发表日期：

    2025年11月17日

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  • Agata Czerwińska,
  • Izabela Karpińska,
  • Piotr Zarzycki,
  • Maciej Matyja,
  • Natalia Dowgiałło-Gornowicz,
  • Paweł Jaworski,
  • Piotr Major

摘要

Introduction

Currently, metabolic bariatric surgery (MBS) is considered the most effective method for achieving substantial and long-term weight-loss in severely obese patients. However, 4 to 40% of bariatric patients do not accomplish optimal results. The study aimed to identify factors contributing to maintain > 50% EWL after MBS at the 10- years observation.

Materials and Methods

This is a retrospective, multicenter cohort study of patients with obesity who completed 10-years follow-up, undergoing primary laparoscopic MBS surgery in 2007–2014. Data came from 5 bariatric centers. Patients were divided into two groups: patients who achieved more than 50% EWL and those who achieved less than 50% EWL. Uni- and multivariable logistic regression were used to identify predictors of optimal results.

Results

Out of 368 analyzed patients the median BMI before the surgery was 42.73 kg/m2. The most common obesity-related diseases were hypertension (HT) (52.72%) and type 2 diabetes mellitus (T2DM) (30.98%). Sleeve gastrectomy was the most frequently performed procedure (65.22%). The median follow-up was 10.90 years. 59,24% patients achieved > 50% EWL. Uni- and multivariable logistic regression analysis confirmed preoperative weigh loss (OR = 1.04; P = 0.03), T2DM (OR = 0.45; P = 0.003), psychiatric history (OR = 0.38; P = 0.01) and one anastomosis gastric bypass (OAGB) (OR = 4.64; P < 0.0001) to have a significant impact on weight loss outcome 10-years after MBS.

Conclusions

In a 10-year follow-up, patients with greater preoperative weight loss may have a better response to surgery. OAGB emerged as promising type of surgery in terms of weight loss. T2DM and psychiatric history are independent predictors of lower %EWL.