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<p>The aim of this study was to evaluate the short-term efficacy of single-anastomosis duodeno-ileostomy with sleeve gastrectomy (SADI-S) using a 400-cm common limb in Chinese patients with obesity of low BMI (&lt;35 kg/m²) and type 2 diabetes (T2D). Sixteen patients who underwent SADI-S between June 2022 and November 2023 were retrospectively analyzed and evaluated at 6 and 12 months postoperatively. The primary outcome was the rate of diabetes remission (HbA1c &lt; 6.5% without antidiabetic medications for ≥ 3 months). Secondary outcomes included excess and total weight loss (EWL and TWL) and nutritional deficiencies. At 12 months postoperatively, 80% of patients achieved diabetic remission, with mean HbA1c decreasing from 8.84 ± 1.55 to 5.93 ± 0.74%. Mean BMI decreased from 30.64 ± 2.29 to 22.91 ± 2.33 kg/m², and EWL and TWL reached 122.12% ± 44.43% and 25.01% ± 8.02%, respectively. Nutritional status remained stable with no cases of hypoalbuminemia and fewer iron and vitamin deficiencies. SADI-S with a 400-cm common limb was effective in achieving glycemic control and weight loss while reducing the risk of nutritional deficiencies in Chinese patients with obesity of low BMI and T2D.</p>

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Short-Term Outcomes of 400-cm Common Limb SADI-S in Chinese Patients with Obesity of BMI < 35 kg/m2 and Type 2 Diabetes

  • 期刊论文

  • 发表日期：

    2025年3月3日

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  • Mengcheng He,
  • Chong Cao,
  • Qiyuan Yao,
  • Rong Hua,
  • Qiwei Shen,
  • Xiaojian Fu,
  • Bo Xu,
  • Yikai Shao

摘要

The aim of this study was to evaluate the short-term efficacy of single-anastomosis duodeno-ileostomy with sleeve gastrectomy (SADI-S) using a 400-cm common limb in Chinese patients with obesity of low BMI (<35 kg/m²) and type 2 diabetes (T2D). Sixteen patients who underwent SADI-S between June 2022 and November 2023 were retrospectively analyzed and evaluated at 6 and 12 months postoperatively. The primary outcome was the rate of diabetes remission (HbA1c < 6.5% without antidiabetic medications for ≥ 3 months). Secondary outcomes included excess and total weight loss (EWL and TWL) and nutritional deficiencies. At 12 months postoperatively, 80% of patients achieved diabetic remission, with mean HbA1c decreasing from 8.84 ± 1.55 to 5.93 ± 0.74%. Mean BMI decreased from 30.64 ± 2.29 to 22.91 ± 2.33 kg/m², and EWL and TWL reached 122.12% ± 44.43% and 25.01% ± 8.02%, respectively. Nutritional status remained stable with no cases of hypoalbuminemia and fewer iron and vitamin deficiencies. SADI-S with a 400-cm common limb was effective in achieving glycemic control and weight loss while reducing the risk of nutritional deficiencies in Chinese patients with obesity of low BMI and T2D.