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<p>Fruit preservation and shelf life extension rely heavily on effective materials, but current methods often fail to combine key functions like antibacterial protection and freshness retention. This study aims to develop a multifunctional hydrogel to address the existing challenges in grape preservation. The hydrogel, termed as CS-<i>se</i>-HA<sup>gel</sup>, was fabricated <i>via</i> Schiff base reactions between dialdehyde chitosan (DACS) and 2,2’-diselanediyldiethanamine (DD)-conjugated hyaluronic acid (DDHA) polymers. Studies found that CS-<i>se</i>-HA<sup>gel</sup> possessed an outstanding swelling ratio, low cytotoxicity, good water retention, and excellent mechanical properties. Besides, it also showed potent antibacterial activity, which prevented the treated grapes from rotting and wrinkling. Significantly, CS-<i>se</i>-HA<sup>gel</sup> also decreased water loss from grapes and maintained their total soluble solid (TSS) and pH stability, prolonging the shelf life of harvested grapes at ambient temperature. Therefore, it could be speculated that CS-<i>se</i>-HA<sup>gel</sup> has potential applications for fruit preservation in the food industry.</p>

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2, 2’-Diselanediyldiethylamine-modified hyaluronic acid/dialdehyde chitosan injectable hydrogel: design, fabrication and fresh-keeping application for postharvest grapes

  • 期刊论文

  • 发表日期：

    2026年4月29日

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  • Xue Yang,
  • Shasha Jiang,
  • Tong Ren,
  • Meng Zhuo,
  • Yanwei Hou,
  • Yingyu Su,
  • Xueyan Hou,
  • Huijuan Yan

摘要

Fruit preservation and shelf life extension rely heavily on effective materials, but current methods often fail to combine key functions like antibacterial protection and freshness retention. This study aims to develop a multifunctional hydrogel to address the existing challenges in grape preservation. The hydrogel, termed as CS-se-HAgel, was fabricated via Schiff base reactions between dialdehyde chitosan (DACS) and 2,2’-diselanediyldiethanamine (DD)-conjugated hyaluronic acid (DDHA) polymers. Studies found that CS-se-HAgel possessed an outstanding swelling ratio, low cytotoxicity, good water retention, and excellent mechanical properties. Besides, it also showed potent antibacterial activity, which prevented the treated grapes from rotting and wrinkling. Significantly, CS-se-HAgel also decreased water loss from grapes and maintained their total soluble solid (TSS) and pH stability, prolonging the shelf life of harvested grapes at ambient temperature. Therefore, it could be speculated that CS-se-HAgel has potential applications for fruit preservation in the food industry.