<p>Zein is a plant-based edible and GRAS grade protein commonly obtained from the byproduct of corn. It is a lipophilic biopolymer owing to the presence of high amounts of nonpolar amino acids. Zein is known for its excellent film-forming, oxygen barrier and thermoplastic properties. The physical properties of zein are favourable for fabricating environmentally friendly packaging materials. The physical and functional properties of zein based packaging can be improved and tuned by adding polymers, plasticizers, nanofillers, plant extracts, and bioactive compounds. Solution casting, electrospray, blown extrusion etc. are the commonly used method to develop zein-based functional film packaging which can be used for food packaging applications. The unique hydrophobic nature of zein is differ from other polymers, fits to use in active packaging film and coating. There are already many reports published on zein based active packaging and unlike previous report, in this review we comprehensively discussed recent advances in zein-based packaging materials preparation and its application in food preservation. Recently published reports suggests that zein-based coating and film can effectively enhance the shelf life of fruits, meat, fish, baked food, dairy products, etc. Therefore, the current review is expected to provide valuable insights to the researcher and food industry regarding the potential of zein-based packaging material.</p> Graphical Abstract <p></p>