The voltammetric determination and electrochemical mechanism of alpha-lipoic acid at a multi-walled carbon nanotube-surfactant modified glassy carbon electrode in the food additive sample

Alpha-lipoic acid (α-LA) is a naturally occurring compound that is both water and fat soluble, functioning as a powerful antioxidant in the body. In this study, multi-walled carbon nanotubes (MWCNTs) with SDS were electrodeposited onto a glassy carbon electrode (GCE) electrochemically. This modified electrode was characterized by electrochemical techniques (EIS, CV). The MWCNT/SDS-modified GCE was utilized for the analysis of α-LA. An electrochemical oxidation mechanism for α-LA was proposed using the developed electrochemical sensor. After optimizing the conditions, the MWCNT/SDS-GCE sensor exhibited a linear response in the concentration range of 0.6–9.0 µM, with a detection limit of 0.15 µM. Additionally, this chemical sensor was effectively utilized for the electrochemical analysis of α-LA in the food additive sample.