Scholarlink

Purpose <p><i>Acanthamoeba</i> spp. can colonize various freshwater habitats. They are the causative agents of granulomatous amoebic encephalitis and can harbor many microorganisms. We studied the presence of <i>Acanthamoeba</i> spp. in the water system of a hemodialysis unit and assessed the potential for transmission to hemodialysis patients.</p> Methods <p>Water samples collected from pretreatment and posttreatment water of the treatment station and from input and output water of the dialysis machines were cultured on non-nutrient agar supplemented with <i>Escherichia coli</i>. Blood samples from dialysis patients in the unit and from a control group in the same hospital were tested for anti-<i>Acanthamoeba</i> IgG antibodies.</p> Results <p><i>Acanthamoeba</i> spp. were found in posttreatment water. They were more commonly found in the input water samples (79.2%), than in the output water samples (16.7%) (<i>p</i> = 0.001). Anti-<i>Acanthamoeba</i> IgG antibodies were present in 32.9% of patients and were absent in the control group (<i>p</i> = 0.002). The duration of hemodialysis was significantly longer in seropositive patients than in seronegative patients (<i>p</i> = 0.008).</p> Conclusion <p>The study highlights the presence of <i>Acanthamoeba</i> spp. in the dialysis system. The relatively high prevalence of anti-<i>Acanthamoeba</i> IgG antibodies and the link between dialysis duration and seropositivity emphasize the importance of rigorous water monitoring.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Acanthamoeba spp. in Dialysis Water: Assessing the Potential Risk of Transmission to Hemodialysis Patients

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年2月7日

查看全文
  • Mona Mohamed Tolba,
  • Heba Elhadad,
  • Shaban Hassan Abu Kabsha,
  • Nesma Seyam El-Kady,
  • Safia Saleh Khalil,
  • Amira Hussein Mohamed,
  • Hend Aly El-Taweel

摘要

Purpose

Acanthamoeba spp. can colonize various freshwater habitats. They are the causative agents of granulomatous amoebic encephalitis and can harbor many microorganisms. We studied the presence of Acanthamoeba spp. in the water system of a hemodialysis unit and assessed the potential for transmission to hemodialysis patients.

Methods

Water samples collected from pretreatment and posttreatment water of the treatment station and from input and output water of the dialysis machines were cultured on non-nutrient agar supplemented with Escherichia coli. Blood samples from dialysis patients in the unit and from a control group in the same hospital were tested for anti-Acanthamoeba IgG antibodies.

Results

Acanthamoeba spp. were found in posttreatment water. They were more commonly found in the input water samples (79.2%), than in the output water samples (16.7%) (p = 0.001). Anti-Acanthamoeba IgG antibodies were present in 32.9% of patients and were absent in the control group (p = 0.002). The duration of hemodialysis was significantly longer in seropositive patients than in seronegative patients (p = 0.008).

Conclusion

The study highlights the presence of Acanthamoeba spp. in the dialysis system. The relatively high prevalence of anti-Acanthamoeba IgG antibodies and the link between dialysis duration and seropositivity emphasize the importance of rigorous water monitoring.