<p>The present article principally studies the effects of different laser diameters and occupancy rates on the surface macro- and micromorphology, wettability, and interfacial bonding properties of TC4 titanium alloy with laser microtexture. The findings of the research indicate that in instances where the area occupancy rate remains constant, an augmentation in the texture diameter is observed to result in an escalation in both the surface roughness, Ra, and the interface bonding force. Conversely, when the diameter of the texture is held constant, an enhancement in surface roughness is evident with an increase in area occupancy. However, the interfacial bonding force demonstrates a pattern of initial increase followed by subsequent decrease. The process of laser surface texturing has been demonstrated to reduce the contact angle of the substrate surface, enhance the hydrophilicity of the substrate surface, suppress the phenomenon of large droplets on the coating surface, and thus improve the surface state of the film layer. However, the impact on the thickness of the AlCrN coating is negligible. The bonding strength of the coating after 200-10 texture treatment reached a maximum of 44.8N, which was 0.96 times higher than that of the untreated coating. Laser microtexturing has been observed to induce element diffusion and transfer between the coating and substrate. The diffusion process is found to be predominantly from the substrate to the coating, with minimal diffusion occurring in the opposite direction. The Al element is enriched on the coating surface, forming the primary working layer, while the Cr element is concentrated at the membrane–substrate interface to establish a transition bonding layer. The AlCrN coating has been shown to form a metallurgical bonding and diffusion adhesion coexistence with the TC4 titanium alloy.</p>