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<p>Cold plasma treatment with nitrogen (CPT/N for short) at room temperature was used in this study to achieve the surface roughness of a high-nitrogen nickel-free stainless steel (HNNFSS) stent for improving the adhesive strength between the drug-eluting coating and the substrate. The effects of CPT/N on the surface properties, corrosion resistance, and biocompatibility of HNNFSS stent were studied, and the adhesive strength between the drug-eluting coating and the stent substrate was further compared before and after CPT/N. The results showed that the CPT/N could increase the surface roughness of HNNFSS from 172.09 to 324.78 Å, improve the wettability by enhancing the polar component from 17.7 to 43.98%, and promote cell proliferation, without reduction of the pitting resistance. It is also proved that CPT/N could effectively increase the adhesive strength between the drug-eluting coating and the stent substrate, mean value from 1.93 to 6.00&#xa0;MPa. It is proposed that CPT/N is a simple, low-cost, and efficient surface treatment method for improving the bonding performance of high-nitrogen nickel-free steel stent with drug coating.</p>

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Effectiveness of Cold Nitrogen Plasma Treatment on Surface Property, Corrosion Resistance, and Coating Adhesion Performance of High-Nitrogen Stainless Steel Stent

  • 期刊论文

  • 发表日期：

    2026年4月10日

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  • Dexiao Liu,
  • Guisong Gu,
  • Jing Ma,
  • Hui Yang,
  • Shanshan Chen

摘要

Cold plasma treatment with nitrogen (CPT/N for short) at room temperature was used in this study to achieve the surface roughness of a high-nitrogen nickel-free stainless steel (HNNFSS) stent for improving the adhesive strength between the drug-eluting coating and the substrate. The effects of CPT/N on the surface properties, corrosion resistance, and biocompatibility of HNNFSS stent were studied, and the adhesive strength between the drug-eluting coating and the stent substrate was further compared before and after CPT/N. The results showed that the CPT/N could increase the surface roughness of HNNFSS from 172.09 to 324.78 Å, improve the wettability by enhancing the polar component from 17.7 to 43.98%, and promote cell proliferation, without reduction of the pitting resistance. It is also proved that CPT/N could effectively increase the adhesive strength between the drug-eluting coating and the stent substrate, mean value from 1.93 to 6.00 MPa. It is proposed that CPT/N is a simple, low-cost, and efficient surface treatment method for improving the bonding performance of high-nitrogen nickel-free steel stent with drug coating.