<p>This study examines the high-temperature compression creep behavior of swaged Al-12Ce and Al-12Ce-0.4Sc (wt.%) alloys to evaluate the influence of Sc on creep resistance. Compression creep tests were conducted in the temperature range of 300–350 °C, with applied stresses of 30-45 MPa for the Al-12Ce and 55-75 MPa for the Al-12Ce-0.4Sc alloy. Microstructural characterization revealed that the addition of 0.4 wt.% Sc refined the pro-eutectic Al₁₁Ce₃ phase, reducing its average length from ~17.53 µm to ~12.23 µm, while simultaneously increasing its volume fraction from ~6.11 vol.% to ~9.18 vol.%. The Al-12Ce alloy exhibited a creep rate of 1.743 × 10⁻⁵ s⁻¹ at 300 °C/45 MPa, whereas the Sc-modified alloy showed a significantly reduced creep rate of 5.55 × 10⁻⁷ s⁻¹ at 75 MPa due to the presence of fine Al₃Sc precipitates. The true stress exponent (<i>n</i> ≈ 4) and apparent activation energy (<i>Q</i>_<i>c</i> = 204.8–225.3 kJ·mol⁻¹) indicate that creep in both alloys is controlled by a dislocation climb mechanism. Overall, Sc addition markedly enhances creep resistance through microstructural refinement and precipitation strengthening.</p>