<p>Understanding the wear behavior of commercially pure titanium (CP-Ti) is essential for ensuring its reliability in aerospace, medical, chemical, and nuclear spent fuel reprocessing plants. This study systematically examines the sliding wear of CP-Ti against Al₂O₃ using a Ball-on-Disc tribometer, focusing on applied loads (2-10 N) and sliding speeds (0.003–0.016&#xa0;m/s). Increasing the loads led to a decrease in the coefficient of friction and an increase in the wear rate. However, the specific wear rate increase was stable at higher loads (8-10&#xa0;N) across all tested speeds. The CP-Ti exhibited two distinct wear mode regimes of mild and severe wear. The mild wear of CP-Ti is dominated by abrasive and oxidative mechanisms at lower loads (2-4 N) at all speeds, and at 6-8 N under lower (0.003&#xa0;m/s) and then at 6 N at 0.006&#xa0;m/s. Severe wear occurred at higher loads (8-10&#xa0;N), with a combination of adhesive/abrasive/oxidative wear mechanisms. The deformation-induced zone beneath the worn surface increases with load and is attributed to work hardening of CP-Ti. The tribological behavior of CP-Ti, including the wear mechanism and submechanisms based on the worn subsurface, wear debris, and the role of the Al₂O₃ counterbody, is presented. The 2D and 3D wear mode maps of CP-Ti are constructed based on the wear rates. The wear database results of wear mode transition from mild to severe wear, along with the wear mechanisms, would support the design of CP-Ti components, highlighting the significant importance of safety and lifespan in applications such as the chemical and nuclear industries.</p>