<p>Q460 high-strength steel is widely used in construction machinery, bridge structures, and marine equipment due to its excellent load-bearing capacity and corrosion resistance. However, its weld metal from traditional laser-MAG welding exhibits coarse grains, uneven microstructure, and insufficient toughness, limiting the reliability of welded structures under harsh service conditions. Vibration-assisted welding technology has been proven to regulate weld molten pool behavior and refine grain structure, providing a potential solution to improving high-strength steel welding quality. To address this, this study proposes a vibration-assisted laser-MAG welding process for Q460 high-strength steel and systematically investigates the effects of vibration frequency (60-100&#xa0;Hz) and acceleration (40-80&#xa0;m/s²) on weld microstructure and mechanical properties. The results show that in terms of microstructure, vibration can refine the weld microstructure, thereby improving the mechanical properties of the weld joints; among the vibration parameters, acceleration exerts a more significant influence on the microstructure than frequency. With respect to mechanical properties, vibration can enhance hardness, with the bottom welding and cover welding achieving optimal performance at vibration frequencies of 100&#xa0;Hz and 80&#xa0;Hz, respectively. The tensile fractures of the welded specimens all occur at the base metal, indicating that vibration exerts a negligible influence on the tensile strength. However, it can increase the elongation to 24.8% and the reduction of area to 64.3%. Vibration enables the weld to obtain a maximum impact absorbed energy of 214.52&#xa0;J and a maximum bending strength of 1,353.83&#xa0;MPa. Analysis indicates that vibration frequency has a more significant influence on weld hardness and bending performance, while vibration acceleration exerts a greater impact on the impact resistance and tensile strain of the welded joints.</p>