<p>CuSn12Ni2 alloy coating was successfully prepared on 45 steel rods by high-speed laser cladding technology (HSLC). The effect of laser power and scanning speed on the forming quality of single-pass cladding layer is studied. When the specific energy range is 7.8 ~ 10.4&#xa0;J·mm⁻² and the overlap rate of multi-pass cladding layer is 40-50%, CuSn12Ni2 coating can be obtained with good bonding to the substrate, low dilution rate, and no defects such as cracks and pores. The microstructure, microhardness, bonding strength, tribological properties, and corrosion resistance of the coating were tested and analyzed. The results show that CuSn12Ni2 coating is mainly composed of <i>α</i>-Cu phase, <i>δ</i> phase (Cu₄₄Sn₁₁), and Ni₃Sn phase. The overall composition of CuSn12Ni2 coating is uniform, the heat-affected zone (HAZ) is small, and the cross-section structure gradually changes from dendrite to equiaxed crystal from bottom to top. The microhardness of the coating is up to 186 HV, and it has stable bonding performance under high load conditions, and the bonding strength is evenly distributed between 280 and 300&#xa0;MPa. At room temperature and 75&#xa0;°C, the average friction coefficient (AFC) of the coating is 0.095 and 0.13, and the specific wear rate (<i>W</i>_s) is 1.0 × 10³ mm³&#xa0;N⁻¹&#xa0;m⁻¹ and 1.4 × 10³ mm³·N⁻¹&#xa0;m⁻¹, respectively. The wear mechanism at room temperature is mainly abrasive wear and a small amount of adhesive wear, while at high temperature, it is mainly abrasive wear and adhesive wear. In 3.5 % NaCl solution, the self-corrosion potential and current density of the coating are 0.13&#xa0;V and 8.419 × 10⁻⁸&#xa0;A&#xa0;cm⁻², respectively. There is a passivation film on the surface of the coating, the radius of the capacitive arc is larger than the surface, and the system impedance is 7.317 × 10⁴&#xa0;Ω&#xa0;cm⁻². CuSn12Ni2 coating improves the wear resistance and corrosion resistance of the substrate.</p>