Investigation of the Mechanical and Corrosive Wear and Biological Behavior of Titanium–5 Manganese–Tricalcium Phosphate Composites Produced by Powder Metallurgy for Hip Implants
摘要
Titanium and its alloys are extensively used in total hip arthroplasty applications. However, conventional titanium implants face challenges such as stiffness mismatch with bone, inadequate elasticity, and low porosity, which can lead to stress shielding and implant failure. To address these limitations, this study aims to achieve an optimal balance between elastic modulus, strength, and plasticity by developing a porous Ti-based alloy (Ti-5Mn-TCP). Titanium (Ti)–manganese (Mn)–tricalcium phosphate (TCP) was selected as the material of interest due to its potential to enhance mechanical and biological properties. The powder metallurgy techniques was employed to fabricate porous structures in composite formulations such as 85Ti-5Mn-10TCP, 65Ti-5Mn-30TCP, and 50Ti-5Mn-45TCP. Microstructural analysis via scanning electron microscope (SEM) and energy-dispersive x-ray (EDX) revealed heterogeneous morphologies with angular particles enhancing friction and mechanical interlocking. Compression tests indicated that the addition of TCP had decreased compressive strength ranging from 432 to 107 MPa. This was coupled with a Young's modulus from 51 to 21 GPa and 65Ti-5Mn-30TCP matches human bone. The results of the porosity tests showed that increasing the TCP led to a reduction in density along with an increase in porosity. Wear and corrosion tests showed that TCP reinforcement exhibited superior wear resistance (1.97, 0.98, 0.24 mm/year) and corrosion resistance (1.97, 0.98 mm/year). Grade 1 on the cell toxicity scale was identified on all three fabricated samples using cytocompatibility tests. The findings of this research highlight the potential of 65Ti-5Mn-30TCP as a promising material for next-generation orthopedic implants with improved biomechanical and biological performance.