<p>K4169 superalloy is usually used in high-temperature environments. Mechanical properties of additively manufactured K4169 superalloy are often lower than those of forgings, which affects its safety of use. Mechanical properties need to be improved by adjusting heat treatment process. Hot isostatic pressing (HIP) technology is a process production technology that combines high temperature and high pressure, uses high temperature and high pressure, metal creep, and plastic deformation to heal defects such as loose and hot cracking inside castings. K4169 superalloy was prepared by laser powder bed fusion (LPBF), and treated by hot isostatic pressing at different temperatures. Microstructure was characterized by metallurgical microscope, scanning electron microscope, and x-ray diffraction analysis. Tensile mechanical properties at room temperature were tested, and influence of different hot isostatic pressing temperatures on the microstructure evolution of K4169 superalloy in LPBF state was explored. Mapping relationship between microstructure and mechanical properties was analyzed. Experimental results show that grains of K4169 alloy after HIP treatment are equiaxed crystals, porosity disappears, and laves phase gradually disappears with the increase of HIP temperature. As grain size increases, tensile strength can reach up to 1117&#xa0;MPa, and the uniform elongation rises to 42.5%.</p>