<p>With the rising demand for energy and the rapid advancement of innovative wearable electronics, developing advanced functional materials for efficient energy harvesting has become essential. In this study, we present the fabrication of a highly flexible, lightweight, and self-poled piezoelectric nanogenerator based on a lab-synthesized V₂O₅ nanocapsule (vanadium pentoxide)-reinforced polyvinylidene fluoride (PVDF) nanocomposite, demonstrating enhanced sensitivity and high output performance. To enhance the V₂O₅ fabrication process, we used the solid-state sintering method, increasing the duration. We confirmed the purity of the V₂O₅ phase and its surface morphology through x-ray diffraction (XRD) and field-emission scanning electron microscopy (FE-SEM), respectively. Thin films of V₂O₅/PVDF were fabricated by systematically varying the V₂O₅ concentrations (0%, 5%, 10%, 15%, 20%) within the PVDF matrix and depositing them onto a glass substrate using the drop-casting technique. Furthermore, we conducted various characterizations including XRD, SEM, and Fourier transform infrared (FTIR) analyses to check the phase morphology, topography, and crystallite size to understand the material properties. The FTIR results confirmed a significant enhancement in the <i>β</i>-phase concentration in 10% V₂O₅/PVDF films. The open-circuit voltage, short-circuit current, and power density measured for the 10 wt.% V₂O₅/PVDF nanogenerator were 15.23&#xa0;V, 4.64 nA, and 47.27&#xa0;μW/cm², respectively. These lead-free composite nanogenerators also exhibited excellent sensitivity in detecting various human body motions, including punching and finger tapping.</p>