Scholarlink

<p>The construction of efficient and convenient chiral enantiomer recognition sensors is of significant importance in the fields of electrochemistry and life sciences. A novel chiral covalent organic polymers (CCOPs) was synthesized using a solvothermal method, and the morphology and structure of the CCOPs material were characterized using transmission electron microscopy (TEM) and X-ray diffraction (XRD) techniques. The CCOPs were utilized to modify a glassy carbon electrode (GCE), and differential pulse voltammetry (DPV) was applied to identify tryptophan (Trp) enantiomers on the CCOPs-modified GCE (CCOPs/GCE). The experimental results indicated that the enantiomers of Trp could be recognized on the CCOPs/GCE, and that the CCOPs/GCE sensor exhibited excellent selectivity, sensitivity, and stability for D-Trp under optimal conditions. Good enantioselectivity was achieved with a recognition efficiency of 3.61 (peak-current ratio of D-Trp to L-Trp) on the CCOPs/GCE. The CCOPs/GCE sensor demonstrated good linearity for D-Trp in the ranges of 0.1–10 µM and 10–300 µM, with a detection limit of 0.05 µM (S/<i>N</i> = 3). The electrochemical sensor developed in this work is characterized by high stability, good repeatability, easy preparation, low cost, and effective differentiation of Trp isomers.</p> Graphical abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Recognition of tryptophan enantiomers on chiral electrochemical sensor based on novel chiral covalent organic polymers

  • 期刊论文

  • 发表日期：

    2026年5月8日

查看全文
  • Ying Nie,
  • Hui Zhang,
  • Zhili Fang

摘要

The construction of efficient and convenient chiral enantiomer recognition sensors is of significant importance in the fields of electrochemistry and life sciences. A novel chiral covalent organic polymers (CCOPs) was synthesized using a solvothermal method, and the morphology and structure of the CCOPs material were characterized using transmission electron microscopy (TEM) and X-ray diffraction (XRD) techniques. The CCOPs were utilized to modify a glassy carbon electrode (GCE), and differential pulse voltammetry (DPV) was applied to identify tryptophan (Trp) enantiomers on the CCOPs-modified GCE (CCOPs/GCE). The experimental results indicated that the enantiomers of Trp could be recognized on the CCOPs/GCE, and that the CCOPs/GCE sensor exhibited excellent selectivity, sensitivity, and stability for D-Trp under optimal conditions. Good enantioselectivity was achieved with a recognition efficiency of 3.61 (peak-current ratio of D-Trp to L-Trp) on the CCOPs/GCE. The CCOPs/GCE sensor demonstrated good linearity for D-Trp in the ranges of 0.1–10 µM and 10–300 µM, with a detection limit of 0.05 µM (S/N = 3). The electrochemical sensor developed in this work is characterized by high stability, good repeatability, easy preparation, low cost, and effective differentiation of Trp isomers.

Graphical abstract