Therapeutische Relevanz – Einfluss eines AKI auf die intensivmedizinische Therapie

Acute kidney injury (AKI) and acute lung injury (ALI) are the most common organ failures in intensive care medicine. AKI significantly impacts morbidity and mortality of affected patients. It often occurs in settings of critical illnesses like sepsis, rather than as a consequence of primary renal diseases. The severity of AKI correlates almost linearly with mortality. It often mirrors the critical illness of the patient but is also an independent predictor of mortality. A variety of conditions in patients under intensive care are associated with the development of AKI. Irrespective of the need for kidney replacement therapy reduction or even loss of kidney function with its wide impact on physiological functions is challenging and requires consideration and a broad adaptation of treatment on intensive care units.