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<p>Adverse childhood experiences (ACEs) are recognized as risk factors for substance use, but evidence from Japan is limited. This study examined the association between ACEs and substance use using data from 30,130 individuals aged 16–81&#xa0;years from the Japan Society and New Tobacco Internet Survey 2022. Outcomes included nicotine, alcohol, benzodiazepine, and illicit drug use. ACE exposure was assessed using a scale adapted for Japan, and analyses were conducted based on both the number and subtypes of ACEs. All ACE subgroups were significantly associated with increased odds of nicotine dependence (RR ≥ 1.15, CI 1.08–1.22), alcohol dependence (RR ≥ 1.52, CI 1.36–1.69), benzodiazepine use (RR ≥ 1.32, CI 1.25–1.40), and illicit drug use (RR ≥ 1.38, CI 1.24–1.53), particularly among those with four or more ACEs. These findings underscore the need for early intervention to prevent further ACE accumulation and reduce substance use risk.</p>

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Association of Adverse Childhood Experiences and Substance Use: Evidence from a Japanese Population Study

  • 期刊论文

  • 发表日期：

    2025年10月29日

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  • Taisuke Yamamoto,
  • Takashi Kimura,
  • Isaku Kurotori,
  • Takahiro Tabuchi,
  • Akiko Tamakoshi

摘要

Adverse childhood experiences (ACEs) are recognized as risk factors for substance use, but evidence from Japan is limited. This study examined the association between ACEs and substance use using data from 30,130 individuals aged 16–81 years from the Japan Society and New Tobacco Internet Survey 2022. Outcomes included nicotine, alcohol, benzodiazepine, and illicit drug use. ACE exposure was assessed using a scale adapted for Japan, and analyses were conducted based on both the number and subtypes of ACEs. All ACE subgroups were significantly associated with increased odds of nicotine dependence (RR ≥ 1.15, CI 1.08–1.22), alcohol dependence (RR ≥ 1.52, CI 1.36–1.69), benzodiazepine use (RR ≥ 1.32, CI 1.25–1.40), and illicit drug use (RR ≥ 1.38, CI 1.24–1.53), particularly among those with four or more ACEs. These findings underscore the need for early intervention to prevent further ACE accumulation and reduce substance use risk.