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<p>Opioid use disorder is a major cause of drug-related harm and mortality. These can be reduced by expanded access to evidence-based and highly effective opioid agonist maintenance treatment or therapy (OMT). There is a lack of consensus on how to assess opioid use disorder treatment outcomes, and key health outcomes are often omitted. We report the results of a Delphi study to produce service user- and public health–centred international consensus guidance for OMT outcomes monitoring. An international group of 110 substance use specialists in 32 countries, including service providers, researchers and people with lived experience of OMT, produced draft guidance over multiple meetings. The guidance includes a service user-reported OMT outcomes questionnaire, based on 26 core questions, plus optional questions, in six domains (treatment, physical health, mental health, social functioning, substance use, quality of life). A Delphi panel of 757 OMT professionals and service users (46%) from 29 countries, of which 40% were female, reviewed the questionnaire over two survey rounds, supporting and improving it (round 2 mean agreement score&#xa0;on a 1-6 Likert scale: 5.2; 95%CI 5.1–5.3). By focusing on service user–reported and public health–centred outcomes of OMT, the OPTIMUS consensus guidance aims to facilitate the communication between service providers and service users and improve the quality of care and the survival, health and quality of life of OMT service users.</p>

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The OPTIMUS International Consensus Guidance for Monitoring User-Reported Outcomes of Opioid Maintenance Treatment: a Delphi Study

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年2月28日

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  • Lucas Wiessing,
  • Deniz Akartuna,
  • Jérôme Antoine,
  • Prakashini Banka-Cullen,
  • María Gabriela Barbaglia,
  • Vendula Belackova,
  • Saed A. S. Belbaisi,
  • Claudia Bernardini,
  • Sonila Bitri,
  • Peter Blanken,
  • Patrizia Carrieri,
  • Saša Čelojević,
  • Catherine Comiskey,
  • Daniel Dacosta-Sánchez,
  • Laura Dale,
  • Geert Dom,
  • Venus Fabricius,
  • Hugo Faria,
  • Gabriele Fischer,
  • Dimos Fotopoulos,
  • Lina Hijazi,
  • Dario Ičanović,
  • Liljana Ignjatova,
  • Nemanja Inić,
  • Britta Jacobsen,
  • Haris Jakavicius,
  • Barbara Janíková,
  • Jana D. Javakhishvili,
  • Zuzana Kamendy,
  • Máté Kapitány-Fövény,
  • Roksana Karczewska,
  • Anna Kiss,
  • Andreas Krasias,
  • Evi Kyprianou,
  • Dominique Lamy,
  • Inga Landsmane,
  • Katy MacLeod,
  • Kirsten Marchand,
  • Thomas Martinelli,
  • Tim Millar,
  • Viktor Mravcik,
  • Naser J. Y. Mustafa,
  • Bojan Nikolovski,
  • Markus Partanen,
  • Mads Uffe Pedersen,
  • Filippo Maria Pericoli,
  • Olena Puhach,
  • Hanna Putkonen,
  • Mariam Razmadze,
  • Rebecca Reifenstein,
  • Perrine Roux,
  • Bernd Schulte,
  • Tanja Schwarz,
  • Paulo Seabra,
  • María Silva,
  • Sinisa Skocibusic,
  • Luis Sordo,
  • Dana Špringelová,
  • Lisa Strada,
  • Beata Stelmaszczyk,
  • Emilis Subata,
  • Kateryna Terykh,
  • Esmeralda Thoma,
  • Marta Torrens,
  • Piotr Tubelewicz,
  • Diāna Vanaga-Arāja,
  • Alexander Y. Walley,
  • Ioanna Yiasemi

摘要

Opioid use disorder is a major cause of drug-related harm and mortality. These can be reduced by expanded access to evidence-based and highly effective opioid agonist maintenance treatment or therapy (OMT). There is a lack of consensus on how to assess opioid use disorder treatment outcomes, and key health outcomes are often omitted. We report the results of a Delphi study to produce service user- and public health–centred international consensus guidance for OMT outcomes monitoring. An international group of 110 substance use specialists in 32 countries, including service providers, researchers and people with lived experience of OMT, produced draft guidance over multiple meetings. The guidance includes a service user-reported OMT outcomes questionnaire, based on 26 core questions, plus optional questions, in six domains (treatment, physical health, mental health, social functioning, substance use, quality of life). A Delphi panel of 757 OMT professionals and service users (46%) from 29 countries, of which 40% were female, reviewed the questionnaire over two survey rounds, supporting and improving it (round 2 mean agreement score on a 1-6 Likert scale: 5.2; 95%CI 5.1–5.3). By focusing on service user–reported and public health–centred outcomes of OMT, the OPTIMUS consensus guidance aims to facilitate the communication between service providers and service users and improve the quality of care and the survival, health and quality of life of OMT service users.