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<p>The proposed research work deals with the designing and analysis of D-shaped photonic crystal fiber (PCF)-based surface plasmonic resonance (SPR) sensor for the detection of range of refractive indices (1.3–1.39), specifically for the sensing of the different types of infected cancer cells and stages of urinary tract infection (UTI). For providing a platform to generate surface plasmons, a plasmonic layered composite of Au/PtSe<sub>2</sub> is introduced at the top surface of PCF. Along with plasmonic films, cladding air holes are incorporated in the PCF structure to perfectly confine the light field and direct it towards the plasmonic components. The comparable analysis of only Au-based and Au/PtSe<sub>2</sub> layered composite-based sensors is done to emphasize the positive effect of PtSe<sub>2</sub> on sensitivity performance. The maximum sensitivity obtained in RI sensing is 12,500&#xa0;nm/RIU, cancer cell sensing is 11,428.57&#xa0;nm/RIU, and UTI detection is 5283.02&#xa0;nm/RIU by employing an Au-based sensor, whereas by incorporating Au/PtSe<sub>2</sub> composite, the sensitivities increased to 21,000&#xa0;nm/RIU (~ 68%), 20,714.29&#xa0;nm/RIU (~ 81%), and 10,094.34&#xa0;nm/RIU (~ 91%), respectively. The overall investigation shows the efficiency and ability of PtSe<sub>2</sub> in enhancing the performance of the sensor.</p>

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Au/PtSe2-Based Surface Plasmon Resonance Photonic Crystal Fiber Biosensor for Cancer and UTI Detection

  • 期刊论文

  • 发表日期：

    2025年8月15日

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  • Akash Khamaru,
  • Ajeet Kumar

摘要

The proposed research work deals with the designing and analysis of D-shaped photonic crystal fiber (PCF)-based surface plasmonic resonance (SPR) sensor for the detection of range of refractive indices (1.3–1.39), specifically for the sensing of the different types of infected cancer cells and stages of urinary tract infection (UTI). For providing a platform to generate surface plasmons, a plasmonic layered composite of Au/PtSe2 is introduced at the top surface of PCF. Along with plasmonic films, cladding air holes are incorporated in the PCF structure to perfectly confine the light field and direct it towards the plasmonic components. The comparable analysis of only Au-based and Au/PtSe2 layered composite-based sensors is done to emphasize the positive effect of PtSe2 on sensitivity performance. The maximum sensitivity obtained in RI sensing is 12,500 nm/RIU, cancer cell sensing is 11,428.57 nm/RIU, and UTI detection is 5283.02 nm/RIU by employing an Au-based sensor, whereas by incorporating Au/PtSe2 composite, the sensitivities increased to 21,000 nm/RIU (~ 68%), 20,714.29 nm/RIU (~ 81%), and 10,094.34 nm/RIU (~ 91%), respectively. The overall investigation shows the efficiency and ability of PtSe2 in enhancing the performance of the sensor.