Scholarlink

<p>This study presents surface plasmon resonance (SPR) biosensor operating in the terahertz (THz) regime for sensitive detection of sperm cells. The sensor demonstrates exceptional performance metrics with a maximum sensitivity of 5000&#xa0;GHz/RIU and figure of merit reaching 67.568 RIU⁻<sup>1</sup>. Comprehensive COMSOL Multiphysics simulations reveal that the sensor exhibits tunable electromagnetic response through modulation of graphene chemical potential, with transmittance values ranging from 97.841% to 56.810% across varying GCP levels. The device shows moderate angular tolerance and demonstrates a resonance frequency shift of 50&#xa0;GHz (from 0.800 THz to 0.775 THz) upon analyte detection. Electric field distribution analysis confirms strong electromagnetic field localization at the resonance frequency of 0.785 THz, indicating optimal energy confinement for enhanced sensing performance. The proposed sensor outperforms several existing designs in terms of sensitivity while offering label-free, real-time detection capabilities specifically optimized for reproductive health diagnostics. Machine learning optimization techniques were employed to predict and enhance the sensor's behavioral characteristics, making it a promising candidate for advanced biomedical sensing applications<b>.</b></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

AI-Augmented Terahertz Biosensor with MXene–Graphene Architecture for Sensitive Sperm Concentration Detection

  • 期刊论文

  • 发表日期：

    2025年6月28日

查看全文
  • Sampath Anbazhagan,
  • Arun Kumar U,
  • Amuthakkannan Rajakannu,
  • Ngaira Mandela

摘要

This study presents surface plasmon resonance (SPR) biosensor operating in the terahertz (THz) regime for sensitive detection of sperm cells. The sensor demonstrates exceptional performance metrics with a maximum sensitivity of 5000 GHz/RIU and figure of merit reaching 67.568 RIU⁻1. Comprehensive COMSOL Multiphysics simulations reveal that the sensor exhibits tunable electromagnetic response through modulation of graphene chemical potential, with transmittance values ranging from 97.841% to 56.810% across varying GCP levels. The device shows moderate angular tolerance and demonstrates a resonance frequency shift of 50 GHz (from 0.800 THz to 0.775 THz) upon analyte detection. Electric field distribution analysis confirms strong electromagnetic field localization at the resonance frequency of 0.785 THz, indicating optimal energy confinement for enhanced sensing performance. The proposed sensor outperforms several existing designs in terms of sensitivity while offering label-free, real-time detection capabilities specifically optimized for reproductive health diagnostics. Machine learning optimization techniques were employed to predict and enhance the sensor's behavioral characteristics, making it a promising candidate for advanced biomedical sensing applications.