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<p>Concerns regarding human health have been raised by cancer, the most common disease on the planet. One of the main arguments for improving treatment outcomes is early discovery. This work proposed and numerically examined a novel surface plasmon resonance (SPR) biosensor using BaF<sub>2</sub> prism and a hybrid structure comprised of copper, CsPbI<sub>3</sub>, and 2D materials in Kretschmann configuration for the quick and precise detection of blood cancer. The thickness of the metal layer, perovskite layer, and several 2D materials as cover layer are examined and optimized for superior performance including high sensitivity, figure of merit (FOM), and minimum reflectance (<i>R</i><sub>min</sub>) of SPR spectrum based on the transfer matrix method. The numerical results show enhanced sensitivity up to 427.85&#xa0;deg/RIU, and FOM as high as 247.31 RIU<sup>−1</sup> is obtained upon suitably optimizing the thickness of each layer. The proposed research surpasses the results of recently reported similar configurations. We expect such a hybrid structure using cost effective Cu as a plasmonic metal with exceptional sensing performance is useful for early detection of blood cancer.</p>

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High-Performance Copper-Based Surface Plasmon Resonance Sensor for the Detection of Blood Cancer Using Perovskite Cesium Lead Iodide and Black Phosphorus

  • 期刊论文

  • 发表日期：

    2025年6月27日

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  • R. Nikhita,
  • N. Priyadharsini,
  • S. M. Habibur Rahman,
  • Z. Jaroszewicz,
  • K. B. Rajesh

摘要

Concerns regarding human health have been raised by cancer, the most common disease on the planet. One of the main arguments for improving treatment outcomes is early discovery. This work proposed and numerically examined a novel surface plasmon resonance (SPR) biosensor using BaF2 prism and a hybrid structure comprised of copper, CsPbI3, and 2D materials in Kretschmann configuration for the quick and precise detection of blood cancer. The thickness of the metal layer, perovskite layer, and several 2D materials as cover layer are examined and optimized for superior performance including high sensitivity, figure of merit (FOM), and minimum reflectance (Rmin) of SPR spectrum based on the transfer matrix method. The numerical results show enhanced sensitivity up to 427.85 deg/RIU, and FOM as high as 247.31 RIU−1 is obtained upon suitably optimizing the thickness of each layer. The proposed research surpasses the results of recently reported similar configurations. We expect such a hybrid structure using cost effective Cu as a plasmonic metal with exceptional sensing performance is useful for early detection of blood cancer.