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<p>Employing surface plasmon resonance (SPR) in a specially designed dual-core photonic crystal fiber (PCF) with double-sided polishing, this study demonstrates a biosensor with superior sensitivity for <i>Bacillus cereus</i> identification. The sensor uses silica as a background material, and the structure is optimized by COMSOL Multiphysics software. Under Y-pol, the refractive index (RI) detection ranges were determined as <i>n</i><sub>a</sub> = 1.31–1.40 for odd mode and <i>n</i><sub>a</sub> = 1.31–1.39 for even mode. The maximum wavelength sensitivity (WS) reached 30,600&#xa0;nm/RIU for even mode and 23,800&#xa0;nm/RIU for odd mode. Within the concentration range of 0.2 × 10<sup>8</sup>–1.4 × 10<sup>8</sup>&#xa0;CFU/ml, both modes demonstrated concentration-dependent variations in WS and figure of merit (FOM), with the even mode exhibiting superior detection performance. In addition to detecting the <i>Bacillus cereus</i> concentration, it can also detect <i>S. aureus</i>, <i>Salmonella</i>, <i>Shigella</i>, <i>E. coli</i>, <i>Vibrio cholerae</i>, and many other common pathogens that cause food poisoning or serious infections.</p>

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Dual-Plasmonic Coupling in Bidirectional SPR-PCF Biosensors: for Detection of Bacillus cereus via Refractive Index Measurement

  • 期刊论文

  • 发表日期：

    2025年6月11日

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  • Licui Ji,
  • Honggang Pan,
  • Zihong Zhao,
  • Qingcheng You,
  • Yukun Zhu,
  • Xu Gao,
  • Xing Wang

摘要

Employing surface plasmon resonance (SPR) in a specially designed dual-core photonic crystal fiber (PCF) with double-sided polishing, this study demonstrates a biosensor with superior sensitivity for Bacillus cereus identification. The sensor uses silica as a background material, and the structure is optimized by COMSOL Multiphysics software. Under Y-pol, the refractive index (RI) detection ranges were determined as na = 1.31–1.40 for odd mode and na = 1.31–1.39 for even mode. The maximum wavelength sensitivity (WS) reached 30,600 nm/RIU for even mode and 23,800 nm/RIU for odd mode. Within the concentration range of 0.2 × 108–1.4 × 108 CFU/ml, both modes demonstrated concentration-dependent variations in WS and figure of merit (FOM), with the even mode exhibiting superior detection performance. In addition to detecting the Bacillus cereus concentration, it can also detect S. aureus, Salmonella, Shigella, E. coli, Vibrio cholerae, and many other common pathogens that cause food poisoning or serious infections.