Design & Analysis of D-Shaped SPR-Based PCF Biosensor for Detecting Glucose in Urine
摘要
This paper presents a D-shaped photonic crystal fiber (PCF) biosensor operating in the range of visible light. It uses surface plasmon resonance (SPR) for the concentration detection of glucose in urine. The basic structure of the proposed sensor is a hexagonal lattice with two rings of circular air holes, where the outer ring is further etched to achieve the D-shaped surface. An Au layer is embedded in the planar outer wrapping of the fiber for plasmonic sensing. A layer of titanium dioxide at the bottom is used to remedy the adhesion problem. The finite element method (FEM) is used with COMSOL Multiphysics to test the wavelength and amplitude interrogation methods for the sensor. Sensor characterization is performed at the glucose concentrations 2.5, 5, 10, and 20 g/dl, corresponding to the refractive index (RI) values of 1.338, 1.341, 1.346, and 1.358. By optimizing properties such as plasmonic layer thickness, air-hole diameter, and pitch, the sensor has attained maximum wavelength and amplitude sensitivity of 3333.33 nm/RIU and 230.4 RIU⁻1, respectively. Additionally, the results show extremely high linearity (R2 = 0.99993) and excellent fabrication tolerance, making it a promising tool for glucose detection applications in urine.