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<p>With an emphasis on detecting the presence of cancer cells within a RI of 1.25 to 1.40, this paper introduces and quantitatively explores the usage of a straightforward plasmonic sensor based on a photonic crystal fiber (PCF) in the visible to near-infrared range for bio-analyte sensing. Using a finite element method (FEM) mode solver technique under the scattering boundary condition with a perfectly matched layer, the proposed sensor’s sensing and guiding properties are studied. Gold (Au), which is chemically nonreactive, and tantalum pentoxide (Ta<InlineEquation ID="IEq5"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="11468_2025_2900_Article_IEq1.gif" Format="GIF" Height="10" Rendition="HTML" Resolution="72" Type="Linedraw" Width="8" /> </InlineMediaObject> <EquationSource Format="TEX">\(_2\)</EquationSource> <EquationSource Format="MATHML"><math> <mmultiscripts> <mrow /> <mn>2</mn> <mrow /> </mmultiscripts> </math></EquationSource> </InlineEquation>O<InlineEquation ID="IEq6"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="11468_2025_2900_Article_IEq2.gif" Format="GIF" Height="10" Rendition="HTML" Resolution="72" Type="Linedraw" Width="8" /> </InlineMediaObject> <EquationSource Format="TEX">\(_5\)</EquationSource> <EquationSource Format="MATHML"><math> <mmultiscripts> <mrow /> <mn>5</mn> <mrow /> </mmultiscripts> </math></EquationSource> </InlineEquation>) are deposited on particular parts of the PCF to ease the challenges and reduce the expense of depositing metal on the whole surface of the PCF. The simulation results reveal that the proposed sensor has the highest amplitude and wavelength sensitivity of 853.52 RIU<InlineEquation ID="IEq7"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="11468_2025_2900_Article_IEq7.gif" Format="GIF" Height="11" Rendition="HTML" Resolution="72" Type="Linedraw" Width="18" /> </InlineMediaObject> <EquationSource Format="TEX">\(^{-1}\)</EquationSource> <EquationSource Format="MATHML"><math> <mmultiscripts> <mrow /> <mrow /> <mrow> <mo>-</mo> <mn>1</mn> </mrow> </mmultiscripts> </math></EquationSource> </InlineEquation> and 21,000 nm/RIU, respectively. Additionally, it allows for a maximum figure of merit and sensor resolution of 233.33 RIU<InlineEquation ID="IEq8"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="11468_2025_2900_Article_IEq7.gif" Format="GIF" Height="11" Rendition="HTML" Resolution="72" Type="Linedraw" Width="18" /> </InlineMediaObject> <EquationSource Format="TEX">\(^{-1}\)</EquationSource> <EquationSource Format="MATHML"><math> <mmultiscripts> <mrow /> <mrow /> <mrow> <mo>-</mo> <mn>1</mn> </mrow> </mmultiscripts> </math></EquationSource> </InlineEquation> and <InlineEquation ID="IEq9"> <InlineMediaObject> <ImageObject Color="BlackWhite" FileRef="11468_2025_2900_Article_IEq9.gif" Format="GIF" Height="17" Rendition="HTML" Resolution="72" Type="Linedraw" Width="62" /> </InlineMediaObject> <EquationSource Format="TEX">\(8 \times 10^{-6}\)</EquationSource> <EquationSource Format="MATHML"><math> <mrow> <mn>8</mn> <mo>×</mo> <msup> <mn>10</mn> <mrow> <mo>-</mo> <mn>6</mn> </mrow> </msup> </mrow> </math></EquationSource> </InlineEquation> RIU, respectively. However, the sensor’s excellent detection capability suggests that it might be utilized to detect a wide variety of chemical substances and biological contaminants.</p>

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Cancer Detection Using Au-Ta\(_2\)O\(_5\)-Coated PCF-Based SPR RI Sensor

  • 期刊论文

  • 发表日期：

    2025年3月26日

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  • A. B. M. Saiduzzaman Rafi,
  • Hasan Sarker,
  • Shahriar Amin,
  • Priyanka Das,
  • Md. Arafat Rahman,
  • Md. Sakib Ikbal,
  • Shajjad Hossen

摘要

With an emphasis on detecting the presence of cancer cells within a RI of 1.25 to 1.40, this paper introduces and quantitatively explores the usage of a straightforward plasmonic sensor based on a photonic crystal fiber (PCF) in the visible to near-infrared range for bio-analyte sensing. Using a finite element method (FEM) mode solver technique under the scattering boundary condition with a perfectly matched layer, the proposed sensor’s sensing and guiding properties are studied. Gold (Au), which is chemically nonreactive, and tantalum pentoxide (Ta \(_2\) 2 O \(_5\) 5 ) are deposited on particular parts of the PCF to ease the challenges and reduce the expense of depositing metal on the whole surface of the PCF. The simulation results reveal that the proposed sensor has the highest amplitude and wavelength sensitivity of 853.52 RIU \(^{-1}\) - 1 and 21,000 nm/RIU, respectively. Additionally, it allows for a maximum figure of merit and sensor resolution of 233.33 RIU \(^{-1}\) - 1 and \(8 \times 10^{-6}\) 8 × 10 - 6 RIU, respectively. However, the sensor’s excellent detection capability suggests that it might be utilized to detect a wide variety of chemical substances and biological contaminants.