Scholarlink

<p>The theoretical and simulation-based investigation of an SPR biosensor for the detection of <i>Escherichia coli</i> (<i>E. coli</i>) bacteria using optimum radiation damping (ORD) has been performed. The sensor structure consists of a calcium fluoride (CaF<sub>2</sub>) prism, silver (Ag) as plasmonic metal, potassium tantalate (KTaO<sub>3</sub>) as an absorption enhancement dielectric layer and poly-<span>l</span>-lysine as an affinity layer. Inclusion of KTaO<sub>3</sub> enhances the evanescent field into the structure, while poly-<span>l</span>-lysine provides practical selectivity to the device. The sensor’s figure of merit (FOM) is optimized by concurrent variation of the Ag layer (<i>t</i><sub><i>M</i></sub>), KTaO<sub>3</sub> layer (<i>t</i><sub><i>A</i></sub>) thicknesses and operating wavelength (<i>λ</i>). An optimized FOM is achieved as 9215 RIU<sup>−1</sup> at <i>t</i><sub><i>M</i></sub> = 47.9&#xa0;nm, <i>t</i><sub><i>A</i></sub> = 3.4&#xa0;nm and <i>λ</i> = 1001&#xa0;nm. This is designated as an ORD condition for the sensor. At ORD, the power loss ratio of 2.78 and the normalized electric field (NEF) enhancement factor of about 1.14 have been achieved. Along with these parametric values, the combined performance factor (CPF) of 29,321.46 RIU<sup>−1</sup> has been obtained. The performance of the sensor is way higher than previously reported designs.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Potassium Tantalate (KTaO3) and Poly-l-Lysine-Assisted Prism-Based SPR Biosensor for E. coli Bacteria Detection under Optimum Radiation Damping

  • 期刊论文

  • 发表日期：

    2025年3月22日

查看全文
  • Sudhir Shukla,
  • Pooja Lohia,
  • D. K. Dwivedi,
  • Adarsh Chandra Mishra

摘要

The theoretical and simulation-based investigation of an SPR biosensor for the detection of Escherichia coli (E. coli) bacteria using optimum radiation damping (ORD) has been performed. The sensor structure consists of a calcium fluoride (CaF2) prism, silver (Ag) as plasmonic metal, potassium tantalate (KTaO3) as an absorption enhancement dielectric layer and poly-l-lysine as an affinity layer. Inclusion of KTaO3 enhances the evanescent field into the structure, while poly-l-lysine provides practical selectivity to the device. The sensor’s figure of merit (FOM) is optimized by concurrent variation of the Ag layer (tM), KTaO3 layer (tA) thicknesses and operating wavelength (λ). An optimized FOM is achieved as 9215 RIU−1 at tM = 47.9 nm, tA = 3.4 nm and λ = 1001 nm. This is designated as an ORD condition for the sensor. At ORD, the power loss ratio of 2.78 and the normalized electric field (NEF) enhancement factor of about 1.14 have been achieved. Along with these parametric values, the combined performance factor (CPF) of 29,321.46 RIU−1 has been obtained. The performance of the sensor is way higher than previously reported designs.