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<p>Developing new devices to the early detection of breast cancer via specific molecules is the key to delivering better breast cancer handling and a greater opportunity for living. Plasmonic nanoparticles (NPs) offer useful potential for early breast cancer detection due to their specific optical properties. These NPs, naturally composed of gold or silver metals, display optical properties like localized surface plasmon resonance (LSPR), where combined oscillations of electrons make intense light scattering and absorption. LSPR enables sensitive detection of biomarkers, including peptides, DNA, aptamers, and other small biomolecules. One useful application of plasmonic NPs is surface-enhanced Raman scattering (SERS), where NPs intensify the Raman signal of molecules. In this review after an introduction of breast cancer biomarkers and plasmonic NPs, a comprehensive study was presented about the application of plasmonic NPs for the primary detection of breast cancer biomarkers and their advantages in this line.</p> Graphical Abstract <p></p>

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Plasmonic Nanoparticles: Enhancing Early Breast Cancer Detection Through Biosensors

  • 期刊论文

  • 发表日期：

    2025年3月3日

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  • Mohamed J. Saadh,
  • Tamara Nazar Saeed,
  • Karar H. Alfarttoosi,
  • Gaurav Sanghvi,
  • R. Roopashree,
  • Vishal Thakur,
  • L. Lakshmi,
  • Zafar Aminov,
  • Waam Mohammed Taher,
  • Mariem Alwan,
  • Mahmood Jasem Jawad,
  • Ali M. Ali Al-Nuaimi

摘要

Developing new devices to the early detection of breast cancer via specific molecules is the key to delivering better breast cancer handling and a greater opportunity for living. Plasmonic nanoparticles (NPs) offer useful potential for early breast cancer detection due to their specific optical properties. These NPs, naturally composed of gold or silver metals, display optical properties like localized surface plasmon resonance (LSPR), where combined oscillations of electrons make intense light scattering and absorption. LSPR enables sensitive detection of biomarkers, including peptides, DNA, aptamers, and other small biomolecules. One useful application of plasmonic NPs is surface-enhanced Raman scattering (SERS), where NPs intensify the Raman signal of molecules. In this review after an introduction of breast cancer biomarkers and plasmonic NPs, a comprehensive study was presented about the application of plasmonic NPs for the primary detection of breast cancer biomarkers and their advantages in this line.

Graphical Abstract