Design of an Efficient Surface Plasmon Resonance Biosensor for Label-Free Detection of Blood Components

Optical refractive index biosensors are susceptible devices for the assessment of various blood components like blood plasma, WBCs, hemoglobin, RBCs, and diabetes mellitus. These biosensors play a crucial role in various fields, including environmental monitoring, pharmaceuticals, biomedical research, and health care. These devices are designed to detect specific biological molecules or chemical compounds by converting their interactions into measurable signals. This manuscript recommends a detached cyclic refractive index biosensor (DCRIB) for the determination of five respective kinds of blood components. The high-rise sensitivity (S) count of 1400 nm/RIU has been noticed for blood plasma, the high-rise quality factor (QF) count is 769.23 for RBCs, the high-rise figure of merit (FOM) count is 540.43 for RBCs, and the minimum determination limit count is 0.0004895 for diabetes cell, along with a high-rise determination range count of 1225.43 for RBCs.