Polarization Selective PCF-Based Plasmonic Biosensor for Multi-Analyte Detection

The proposed miniaturized biosensor, the dual-channel multi-analyte single polarization (DCSP) photonic crystal fiber (PCF) sensor, offers real-time measuring and high sensitivity, making it a promising candidate for future sensing devices. It was structured using the stack-and-draw technique to show the sensor practical feasibility. The DCSP PCF sensor offers maximum wavelength and amplitude sensitivities of 11,000 nm/RIU and 807 RIU⁻¹, respectively in both channels for the analyte refractive index (RI) of n_a = 1.33 to 1.41. This DCSP PCF sensor has a birefringence of 11.2 \(\times {10}^{-4}\) $\times {10}^{-4}$ . The use of DCSP PCF sensors improves the sensitivity to wavelength in detecting multiple analytes in real time. These sensors are suitable for biosensing applications, especially when working with small sample sizes. Additionally, DCSP PCF sensors operate at a single polarization, resulting in lower confinement loss and better wavelength resolution, which enhances their performance. These findings suggest that DCSP PCF sensors have the potential to enhance future sensing technology and improve the detection of diseases and liquid substances.