<p>Loess landslides caused by the freeze-thaw cycle (FTC) have become increasingly frequent. In this study, a typical loess landslide in the seasonal freeze-thaw area was taken as the research object. Triaxial creep tests and scanning electron microscope tests were conducted on the undisturbed loess after FTC. The effects of FTC on the creep characteristics, long-term strength, and microstructure of loess were revealed, and the mechanism of FTC-induced loess landslides was discussed as well. The results show that (1) after FTC, the creep deformation of the sample noticeably increases, and the influence of FTC on the shallow loess is greater. (2) The long-term strength of loess after FTC obviously decreases. As the FTC times rise, the long-term strength initially declines, then increases, and then decreases again. The deterioration effect of FTC on shallow loess is more pronounced. With the increase in moisture content, the long-term strength of loess decreases, and the FTC action gradually weakens the strength difference caused by the change in moisture content. (3) The microstructural analysis of loess samples revealed that FTC results in the change of loess microstructure, the weakening of particle cementation, and the instability of particle contact. (4) FTC leads to the accumulation and evacuation cycle of groundwater in the slope. The formation process of freeze-thaw loess landslides is divided into initial stability stage, freeze-thaw deterioration stage, fracture development, and sliding surface formation stage and slope instability stage. The research results provide a new understanding for the study of loess creep characteristics and the formation mechanism of loess landslides.</p>