Scholarlink

<p>The exposome is defined as the cumulative lifetime exposure to exogenous environmental factors and their corresponding biological responses, thereby providing a holistic framework for elucidating the complex interplay between environmental determinants and human health outcomes. Understanding these complex interactions is important for identifying the causes of diseases and associated risk factors. Recent advances in analytical methodologies employed in exposomics, including mass spectrometry and sensor-based platforms, have significantly expanded our capacity to identify and quantify both external exposures and internal biological responses. This review explores recent advancements and practical applications of these techniques in environmental health studies, with a focus on their role in detecting and characterizing complex exposure patterns. Additionally, we discuss the challenges in exposome research and propose strategies to improve its application, thereby reinforcing the potential of the exposome paradigm in advancing precision public health.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Exposomics-oriented environmental analytical chemistry: progress and challenges

  • 期刊论文

  • 发表日期：

    2025年9月11日

查看全文
  • Hao Yu,
  • Yanhuan Zhu,
  • Yacong Liu,
  • Yinhao Li,
  • Si Li,
  • Honglei Sun,
  • Xian-En Zhao,
  • Yong Li,
  • Qian Liu,
  • Guibin Jiang

摘要

The exposome is defined as the cumulative lifetime exposure to exogenous environmental factors and their corresponding biological responses, thereby providing a holistic framework for elucidating the complex interplay between environmental determinants and human health outcomes. Understanding these complex interactions is important for identifying the causes of diseases and associated risk factors. Recent advances in analytical methodologies employed in exposomics, including mass spectrometry and sensor-based platforms, have significantly expanded our capacity to identify and quantify both external exposures and internal biological responses. This review explores recent advancements and practical applications of these techniques in environmental health studies, with a focus on their role in detecting and characterizing complex exposure patterns. Additionally, we discuss the challenges in exposome research and propose strategies to improve its application, thereby reinforcing the potential of the exposome paradigm in advancing precision public health.