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Asymmetric construction of axial and planar chirality with N-heterocyclic carbene (NHC) organocatalysis

  • Meng Zhang,
  • Xiaoqun Yang,
  • Xiaolin Peng,
  • Xiangyang Li,
  • Zhichao Jin

摘要

N-heterocyclic carbene (NHC) organocatalytic reactions that have been developed for asymmetric construction of axial and planar chirality are systematically summarized and discussed in this review. The challenges and limitations inherent to this highly reactive research field are highlighted towards the end of the review. Additionally, based on our understanding of the current advancements in NHC organocatalysis, we propose potential future directions for further exploration.