Recent progress in sulfonyl fluoride synthesis via the radical sulfur dioxide insertion and fluorination strategy

Sulfonyl fluoride compounds, as the key components for sulfur(VI) fluoride exchange (SuFEx) reaction, are characterized by their high chemical stability yet can be selectively activated under specific conditions to enable efficient chemical bonding and connections. This unique capability has garnered significant interest across various domains. Many strategies have been developed for the synthesis of sulfonyl fluoride compounds. This review focuses on the latest advancements in synthesizing these compounds using the radical sulfur dioxide insertion and fluorination (RSIF) strategy, underscoring the versatility and efficacy of the RSIF strategy in constructing sulfonyl fluoride compounds.