<p>Metacognitive skills are key transversal skills, strongly linked to academic achievement and essential for effective lifelong learning. They are widely recognized to underpin many of the core competencies required for effective social and professional participation, including core competencies such as critical thinking, problem-solving, and self-awareness, highlighted by United Nations Educational, Scientific and Cultural Organization (UNESCO) as key to Education for Sustainable Development. Digital learning technologies and virtual learning environments increasingly form a core strategic dimension of teaching and learning within Higher Education, however effectively harnessing them to enhance student learning remains challenging. This paper presents the Metacognition Design Framework, an evidence-based learning design that scaffolds the development of metacognitive skills in students through blended learning. It draws on the tools available within the virtual learning environment to provide a unique, and potentially powerful, opportunity to extend ‘metacognitive influence’ on student activity and learning outside standard class times with realistic levels of staff input. The design provides clarity for planning accessible learning interventions, their linkage with appropriate technology, and for guiding how face-to-face and online, or fully online, components interrelate. It also delivers an effective conduit to convey information in a practical format that readily permits adaptation to local contexts. Overall, it offers a practical way to re-frame educators as designers, increasing educator design capacity and the effective deployment of technology to enhance learning, at the same time targeting a learning outcome with high potential impact.</p>